Enum: Tissue
URI: [bican:Tissue](https://identifiers.org/brain-bican/vocab/Tissue)
## Permissible Values
| Value | Meaning | Description |
| --- | --- | --- |
| adipose | UBERON:0001013 | Portion of connective tissue composed of adipocytes enmeshed in areolar tissu... |
| adrenal | UBERON:0018303 | Tissue that is part of some adrenal gland |
| anus | UBERON:0001245 | Orifice at the opposite end of an animal's digestive tract from the mouth |
| aorta | UBERON:0000947 | The main trunk of the systemic arterial system that carries blood from the he... |
| appendix | UBERON:0001154 | A blind-ended tube connected to the cecum, from which it develops embryologic... |
| artery | UBERON:0001637 | An epithelial tube or tree of tibes that transports blood away from the heart |
| ascending colon | UBERON:0001156 | Section of colon which is distal to the cecum and proximal to the transversec... |
| astrocytes | CL:0000127 | A class of large neuroglial (macroglial) cells in the central nervous system ... |
| bladder | UBERON:0001255 | Distensible musculomembranous organ situated in the anterior part of the pelv... |
| bone rib | UBERON:0002228 | An intersegmental rod-shaped bone that forms in the peritoneal membrane and a... |
| breast | UBERON:0000310 | The upper ventral region of the torso of an organism |
| bronchus | UBERON:0002185 | The upper conducting airways of the lung; these airways arise from the termin... |
| cervical spinal cord | UBERON:0002726 | A spinal cord segment that adjacent_to a cervical region |
| colon ascending | UBERON:0001156 | Section of colon which is distal to the cecum and proximal to the transversec... |
| colon descending | UBERON:0001158 | The portion of the colon between the left colic flexure and the sigmoid colon... |
| CSF | UBERON:0001359 | A clear, colorless, bodily fluid, that occupies the subarachnoid space and th... |
| DRG cervical | UBERON:0002834 | A group of nerve cell bodies located on the dorsal spinal roots within the ve... |
| DRG sacral | UBERON:0002837 | A group of nerve cell bodies located on the dorsal spinal roots within the ve... |
| DRG thoracic | UBERON:0002835 | A dorsal root ganglion that is part of a thorax |
| diaphragm | UBERON:0001103 | A thin musculomebranous barrier that separates the abdominal and thoracic cav... |
| DNA | NCIT:C449 | A long linear double-stranded polymer formed from nucleotides attached to a d... |
| DRG lumbar | UBERON:0002836 | The group of nerve cell bodies located on the dorsal spinal roots within the ... |
| duodenum | UBERON:0002114 | The first part of the small intestine |
| esophagus | UBERON:0001043 | Tube that connects the pharynx to the stomach |
| eyes | UBERON:0000970 | An organ that detects light |
| fallopian tube | UBERON:0003889 | Initial section of the oviduct through which the ova pass from the ovary to t... |
| fibroblasts | CL:0000057 | A connective tissue cell which secretes an extracellular matrix rich in colla... |
| gallbladder | UBERON:0002110 | An organ that aids digestion and stores bile produced by the liver |
| hair | UBERON:0001037 | A filament, mostly protein, that grows from follicles found in the dermis |
| heart | UBERON:0000948 | A myogenic muscular circulatory organ found in the vertebrate cardiovascular ... |
| ileum | UBERON:0002116 | The portion of the small intestine that extends from the jejunum to the colon |
| jejunum | UBERON:0002115 | The portion of the small intestine that extends from the duodenum to the ileu... |
| kidney | UBERON:0002113 | A paired organ of the urinary tract that produces urine and maintains bodily ... |
| liver | UBERON:0002107 | An exocrine gland which secretes bile and functions in metabolism of protein ... |
| long bone | UBERON:0002495 | A long bone is a bone that has a shaft and 2 ends and is longer than it is wi... |
| lumbar spinal cord | UBERON:0002792 | |
| lung | UBERON:0002048 | Respiration organ that develops as an outpocketing of the esophagus |
| lymph node | UBERON:0000029 | Any of the rounded masses of lymphoid tissue that are surrounded by a capsule... |
| middle ear bone | UBERON:0001686 | One of 3 small bones contained within the middle ear space and serve to trans... |
| nail | UBERON:0001705 | A horn-like keratin structure covering the dorsal aspect of the terminal phal... |
| ovary | UBERON:0000992 | The gonad of a female organism which contains germ cells |
| pancreas | UBERON:0001264 | An endoderm derived structure that produces precursors of digestive enzymes a... |
| peripheral nerve | UBERON:0001021 | An enclosed, cable-like bundle of axons in the peripheral nervous system orig... |
| pineal | UBERON:0001905 | A midline, cone like structure located in the dorso-caudal roof of the 3rd ve... |
| pituitary | UBERON:0000007 | The pituitary gland is an endocrine gland that secretes hormones that regulat... |
| placenta | UBERON:0001987 | Organ of metabolic interchange between fetus and mother, partly of embryonic ... |
| plasma | UBERON:0001969 | The liquid component of blood, in which erythrocytes are suspended |
| prostate | UBERON:0002367 | The prostate gland is a partly muscular, partly glandular body that is situat... |
| psoas muscle | UBERON:0008450 | A powerful flexor of the thigh at the hip joint (psoas major) and a weak flex... |
| RBC | CL:0000232 | A red blood cell |
| RNA | CHEBI:33697 | High molecular weight, linear polymers, composed of nucleotides containing ri... |
| sacral spinal cord | UBERON:0005843 | A spinal cord segment that adjacent_to a sacral region |
| serum | UBERON:0001977 | The portion of blood plasma that excludes clotting factors |
| skin | UBERON:0002097 | The organ covering the body that consists of the dermis and epidermis |
| spleen | UBERON:0002106 | The organ that functions to filter blood and to store red corpuscles and plat... |
| stomach | UBERON:0000945 | An expanded region of the vertebrate alimentary tract that serves as a food s... |
| systemic tissue | UBERON:0002384 | Tissue with cells that deposit non-polarized extracellular matrix including c... |
| temporalis muscle | UBERON:0001598 | Pharyngeal arch 1 muscle that is innervated by the deep temporal branches of ... |
| testicle | UBERON:0000473 | A typically paired male reproductive gland that produces sperm and that in mo... |
| thoracic spinal cord | UBERON:0003038 | The thoracic nerves are the spinal nerves emerging from the thoracic vertebra... |
| thymus | UBERON:0002370 | Anatomical structure of largely lymphoid tissue that functions in cell-mediat... |
| thyroid | UBERON:0002046 | A two-lobed endocrine gland found in all vertebrates, located in front of and... |
| tissue | UBERON:0000479 | Multicellular anatomical structure that consists of many cells of one or a fe... |
| tissue-other | None | |
| tongue | UBERON:0001723 | A fleshy movable process of the floor of the mouths of most vertebrates that ... |
| tonsil | UBERON:0002372 | Either of the two small almond-shaped masses of lymph tissue found on either ... |
| trachea | UBERON:0003126 | The trachea is the portion of the airway that attaches to the bronchi as it b... |
| umbilical cord | UBERON:0002331 | The connecting cord from the developing embryo to the placenta |
| ureter | UBERON:0000056 | Muscular duct that propels urine from the kidneys to the urinary bladder, or ... |
| urinary bladder | UBERON:0001255 | Distensible musculomembranous organ situated in the anterior part of the pelv... |
| urine | UBERON:0001088 | Excretion that is the output of a kidney |
| uterus | UBERON:0000995 | The female muscular organ of gestation in which the developing embryo or fetu... |
| vein | UBERON:0001638 | Any of the tubular branching vessels that carry blood from the capillaries to... |
| vitreous | None | |
| vitreous humor | UBERON:0001797 | A transparent, semigelatinous substance that fills the cavity behind the crys... |
| whole blood | CL:0000738 | An achromatic cell of the myeloid or lymphoid lineages capable of ameboid mov... |
## Slots
| Name | Description |
| --- | --- |
| [tissue_type](tissue_type.md) | The type of non-brain tissues |
## Identifier and Mapping Information
### Schema Source
* from schema: https://w3id.org/brain-bican/donor
## LinkML Source
name: tissue
from_schema: https://w3id.org/brain-bican/donor
rank: 1000
permissible_values:
adipose:
text: adipose
description: Portion of connective tissue composed of adipocytes enmeshed in areolar
tissue.
meaning: UBERON:0001013
adrenal:
text: adrenal
description: Tissue that is part of some adrenal gland.
meaning: UBERON:0018303
anus:
text: anus
description: 'Orifice at the opposite end of an animal''s digestive tract from
the mouth. Its function is to expel feces, unwanted semi-solid matter produced
during digestion, which, depending on the type of animal, may be one or more
of: matter which the animal cannot digest, such as bones; food material after
all the nutrients have been extracted, for example cellulose or lignin; ingested
matter which would be toxic if it remained in the digestive tract; and dead
or excess gut bacteria and other endosymbionts.'
meaning: UBERON:0001245
aorta:
text: aorta
description: The main trunk of the systemic arterial system that carries blood
from the heart to all the organs and other structures of the body, bringing
oxygenated blood to all parts of the body in the systemic circulation.
meaning: UBERON:0000947
appendix:
text: appendix
description: A blind-ended tube connected to the cecum, from which it develops
embryologically.
meaning: UBERON:0001154
artery:
text: artery
description: An epithelial tube or tree of tibes that transports blood away from
the heart.
meaning: UBERON:0001637
ascending colon:
text: ascending colon
description: Section of colon which is distal to the cecum and proximal to the
transversecolon.
meaning: UBERON:0001156
astrocytes:
text: astrocytes
description: A class of large neuroglial (macroglial) cells in the central nervous
system - the largest and most numerous neuroglial cells in the brain and spinal
cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes,
including those with 'end feet' which form the glial (limiting) membrane and
directly and indirectly contribute to the blood-brain barrier. They regulate
the extracellular ionic and chemical environment, and 'reactive astrocytes'
(along with microglia) respond to injury. Astrocytes are reportedly CD68-negative,
CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive,
GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive.
meaning: CL:0000127
bladder:
text: bladder
description: Distensible musculomembranous organ situated in the anterior part
of the pelvic cavity in which urine collects before excretion.
meaning: UBERON:0001255
bone rib:
text: bone rib
description: An intersegmental rod-shaped bone that forms in the peritoneal membrane
and attach to the vertebral parapophyses.
meaning: UBERON:0002228
breast:
text: breast
description: The upper ventral region of the torso of an organism.
meaning: UBERON:0000310
bronchus:
text: bronchus
description: The upper conducting airways of the lung; these airways arise from
the terminus of the trachea.
meaning: UBERON:0002185
cervical spinal cord:
text: cervical spinal cord
description: A spinal cord segment that adjacent_to a cervical region.
meaning: UBERON:0002726
colon ascending:
text: colon ascending
description: Section of colon which is distal to the cecum and proximal to the
transversecolon.
meaning: UBERON:0001156
colon descending:
text: colon descending
description: The portion of the colon between the left colic flexure and the sigmoid
colon at the pelvic brim; the portion of the descending colon lying in the left
iliac fossa is sometimes called the iliac colon.
meaning: UBERON:0001158
CSF:
text: CSF
description: A clear, colorless, bodily fluid, that occupies the subarachnoid
space and the ventricular system around and inside the brain and spinal cord.
meaning: UBERON:0001359
DRG cervical:
text: DRG cervical
description: A group of nerve cell bodies located on the dorsal spinal roots within
the vertebral column at the level of the cervical vertebrae.
meaning: UBERON:0002834
DRG sacral:
text: DRG sacral
description: A group of nerve cell bodies located on the dorsal spinal roots within
the vertebral column at the level of the sacral vertebrae.
meaning: UBERON:0002837
DRG thoracic:
text: DRG thoracic
description: A dorsal root ganglion that is part of a thorax.
meaning: UBERON:0002835
diaphragm:
text: diaphragm
description: A thin musculomebranous barrier that separates the abdominal and
thoracic cavities. Often used for breathing control.
meaning: UBERON:0001103
DNA:
text: DNA
description: A long linear double-stranded polymer formed from nucleotides attached
to a deoxyribose backbone and found in the nucleus of a cell; associated with
the transmission of genetic information.
meaning: NCIT:C449
DRG lumbar:
text: DRG lumbar
description: The group of nerve cell bodies located on the dorsal spinal roots
within the vertebral column at the level of the lumbar vertebrae.
meaning: UBERON:0002836
duodenum:
text: duodenum
description: The first part of the small intestine. At the junction of the stomach
and the duodenum the alimentary canal is inflected. The duodenum first goes
anteriorly for a short distance, turns dorsally, and eventually caudally, thus
it is a U-shaped structure with two horizontal sections (a ventral and a dorsal
one).
meaning: UBERON:0002114
esophagus:
text: esophagus
description: Tube that connects the pharynx to the stomach. In mammals, the oesophagus
connects the buccal cavity with the stomach. The stratified squamous non-keratinised
epithelium lining the buccal cavity is continued through the pharynx down into
the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric
mucosa and covered by peritoneum. The main body of the oesophagus is lined with
small, simple mucous glands. Each gland opens into the lumen by a long duct
which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter
is situated at the point where the oesophagus enters the stomach to prevent
gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching
stratified epithelia of the oesophagus, where they can cause inflammation and
irritation (Wilson and Washington, 1989; Brown et al., 1993).
meaning: UBERON:0001043
eyes:
text: eyes
description: An organ that detects light.
meaning: UBERON:0000970
fallopian tube:
text: fallopian tube
description: Initial section of the oviduct through which the ova pass from the
ovary to the uterus.
meaning: UBERON:0003889
fibroblasts:
text: fibroblasts
description: A connective tissue cell which secretes an extracellular matrix rich
in collagen and other macromolecules. Flattened and irregular in outline with
branching processes; appear fusiform or spindle-shaped. These cells may be vimentin-positive,
fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen
III-positive, and alpha-SMA-negative.
meaning: CL:0000057
gallbladder:
text: gallbladder
description: An organ that aids digestion and stores bile produced by the liver.
Rats do not have a gallbladder, but produce bile. The bile flows directly from
the liver through the (hepatic) bile duct into the small intestine (Hebel and
Stromberg, 1988).
meaning: UBERON:0002110
hair:
text: hair
description: A filament, mostly protein, that grows from follicles found in the
dermis.
meaning: UBERON:0001037
heart:
text: heart
description: A myogenic muscular circulatory organ found in the vertebrate cardiovascular
system composed of chambers of cardiac muscle. It is the primary circulatory
organ. Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian
heart is formed after metamorphosis as a simple tube-like structure with a single-layered
myoepithelium that is continuous with a single-layered pericar- dial wall. It
lacks chambers and endocardium.... The innovation of the chambered heart was
a key event in vertebrate evolution, because the chambered heart generates one-way
blood flow with high pressure, a critical requirement for the efficient blood
supply of large-body vertebrates... all extant vertebrates have hearts with
two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
meaning: UBERON:0000948
ileum:
text: ileum
description: The portion of the small intestine that extends from the jejunum
to the colon.
meaning: UBERON:0002116
jejunum:
text: jejunum
description: The portion of the small intestine that extends from the duodenum
to the ileum.
meaning: UBERON:0002115
kidney:
text: kidney
description: A paired organ of the urinary tract that produces urine and maintains
bodily fluid homeostasis, blood pressure, pH levels, red blood cell production
and skeleton mineralization.
meaning: UBERON:0002113
liver:
text: liver
description: An exocrine gland which secretes bile and functions in metabolism
of protein and carbohydrate and fat, synthesizes substances involved in the
clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances,
stores glycogen, and breaks down worn-out erythrocytes.
meaning: UBERON:0002107
long bone:
text: long bone
description: A long bone is a bone that has a shaft and 2 ends and is longer than
it is wide. Long bones have a thick outside layer of compact bone and an inner
medullary cavity containing bone marrow. The ends of a long bone contain spongy
bone and an epiphyseal plate or line depending on the stage of development.
The epiphyseal plate is a hyaline cartilage, where new bone growth takes place,
lengthening the bone prior to adulthood. Bone lengthening ceases when this cartilage
is lost, leaving a remnant referred to as an epiphyseal line.
meaning: UBERON:0002495
lumbar spinal cord:
text: lumbar spinal cord
meaning: UBERON:0002792
lung:
text: lung
description: Respiration organ that develops as an outpocketing of the esophagus.
meaning: UBERON:0002048
lymph node:
text: lymph node
description: Any of the rounded masses of lymphoid tissue that are surrounded
by a capsule of connective tissue, are distributed along the lymphatic vessels,
and contain numerous lymphocytes which filter the flow of lymph.
meaning: UBERON:0000029
middle ear bone:
text: middle ear bone
description: One of 3 small bones contained within the middle ear space and serve
to transmit sounds from the air to the fluid-filled labyrinth. The absence of
the auditory ossicles would constitute a moderate-to-severe hearing loss. The
term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory
ossicles, though the term may refer to any small bone throughout the body.
meaning: UBERON:0001686
nail:
text: nail
description: A horn-like keratin structure covering the dorsal aspect of the terminal
phalanges of fingers and toes.
meaning: UBERON:0001705
ovary:
text: ovary
description: The gonad of a female organism which contains germ cells.
meaning: UBERON:0000992
pancreas:
text: pancreas
description: An endoderm derived structure that produces precursors of digestive
enzymes and blood glucose regulating hormones.
meaning: UBERON:0001264
peripheral nerve:
text: peripheral nerve
description: An enclosed, cable-like bundle of axons in the peripheral nervous
system originating in a nerve root in the central nervous system (or a condensed
nervous structure) connecting with peripheral structures.
meaning: UBERON:0001021
pineal:
text: pineal
description: A midline, cone like structure located in the dorso-caudal roof of
the 3rd ventricle, attached by peduncles to the habenular and posterior commissures.
The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal
cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399).
meaning: UBERON:0001905
pituitary:
text: pituitary
description: The pituitary gland is an endocrine gland that secretes hormones
that regulate many other glands.
meaning: UBERON:0000007
placenta:
text: placenta
description: Organ of metabolic interchange between fetus and mother, partly of
embryonic origin and partly of maternal origin[GO]. The fetal portion of the
placenta is known as the villous chorion. The maternal portion is known as the
decidua basalis. The two portions are held together by anchoring villi that
are anchored to the decidua basalis by the cytotrophoblastic shell. Marsupials
possess only a rudimentary yolk-type placenta, with reduced nutrient and oxygen
exchanging capabilities.
meaning: UBERON:0001987
plasma:
text: plasma
description: The liquid component of blood, in which erythrocytes are suspended.
meaning: UBERON:0001969
prostate:
text: prostate
description: The prostate gland is a partly muscular, partly glandular body that
is situated near the base of the mammalian male urethra and secretes an alkaline
viscid fluid which is a major constituent of the ejaculatory fluid.
meaning: UBERON:0002367
psoas muscle:
text: psoas muscle
description: A powerful flexor of the thigh at the hip joint (psoas major) and
a weak flexor of the trunk and lumbar spinal column (psoas minor). Psoas is
derived from the Greek 'psoa', the plural meaning 'muscles of the loin'. It
is a common site of infection manifesting as abscess (PSOAS ABSCESS). The psoas
muscles and their fibers are also used frequently in experiments in muscle physiology.
meaning: UBERON:0008450
RBC:
text: RBC
description: A red blood cell. In mammals, mature erythrocytes are biconcave disks
containing hemoglobin whose function is to transport oxygen.
meaning: CL:0000232
RNA:
text: RNA
description: High molecular weight, linear polymers, composed of nucleotides containing
ribose and linked by phosphodiester bonds; RNA is central to the synthesis of
proteins.
meaning: CHEBI:33697
sacral spinal cord:
text: sacral spinal cord
description: A spinal cord segment that adjacent_to a sacral region.
meaning: UBERON:0005843
serum:
text: serum
description: The portion of blood plasma that excludes clotting factors.
meaning: UBERON:0001977
skin:
text: skin
description: The organ covering the body that consists of the dermis and epidermis.
meaning: UBERON:0002097
spleen:
text: spleen
description: The organ that functions to filter blood and to store red corpuscles
and platelets.
meaning: UBERON:0002106
stomach:
text: stomach
description: An expanded region of the vertebrate alimentary tract that serves
as a food storage compartment and digestive organ. A stomach is lined, in whole
or in part by a glandular epithelium.
meaning: UBERON:0000945
systemic tissue:
text: systemic tissue
description: Tissue with cells that deposit non-polarized extracellular matrix
including connective tissue fibers and ground substance.
meaning: UBERON:0002384
temporalis muscle:
text: temporalis muscle
description: Pharyngeal arch 1 muscle that is innervated by the deep temporal
branches of the trigeminal nerve and attaches to the wall of the braincase (including
the cranial vault) and mandible.
meaning: UBERON:0001598
testicle:
text: testicle
description: A typically paired male reproductive gland that produces sperm and
that in most mammals is contained within the scrotum at sexual maturity.
meaning: UBERON:0000473
thoracic spinal cord:
text: thoracic spinal cord
description: The thoracic nerves are the spinal nerves emerging from the thoracic
vertebrae.
meaning: UBERON:0003038
thymus:
text: thymus
description: Anatomical structure of largely lymphoid tissue that functions in
cell-mediated immunity by being the site where T cells develop.
meaning: UBERON:0002370
thyroid:
text: thyroid
description: A two-lobed endocrine gland found in all vertebrates, located in
front of and on either side of the trachea in humans, and producing various
hormones, such as triiodothyronine and calcitonin.
meaning: UBERON:0002046
tissue:
text: tissue
description: Multicellular anatomical structure that consists of many cells of
one or a few types, arranged in an extracellular matrix such that their long-range
organisation is at least partly a repetition of their short-range organisation.
meaning: UBERON:0000479
tissue-other:
text: tissue-other
tongue:
text: tongue
description: A fleshy movable process of the floor of the mouths of most vertebrates
that bears sensory end organs and small glands and functions especially in taking
and swallowing food and in humans as a speech organ.
meaning: UBERON:0001723
tonsil:
text: tonsil
description: Either of the two small almond-shaped masses of lymph tissue found
on either side of the oropharynx.
meaning: UBERON:0002372
trachea:
text: trachea
description: The trachea is the portion of the airway that attaches to the bronchi
as it branches.
meaning: UBERON:0003126
umbilical cord:
text: umbilical cord
description: The connecting cord from the developing embryo to the placenta.
meaning: UBERON:0002331
ureter:
text: ureter
description: Muscular duct that propels urine from the kidneys to the urinary
bladder, or related organs.
meaning: UBERON:0000056
urinary bladder:
text: urinary bladder
description: Distensible musculomembranous organ situated in the anterior part
of the pelvic cavity in which urine collects before excretion.
meaning: UBERON:0001255
urine:
text: urine
description: Excretion that is the output of a kidney.
meaning: UBERON:0001088
uterus:
text: uterus
description: The female muscular organ of gestation in which the developing embryo
or fetus is nourished until birth.
meaning: UBERON:0000995
vein:
text: vein
description: Any of the tubular branching vessels that carry blood from the capillaries
toward the heart.
meaning: UBERON:0001638
vitreous:
text: vitreous
vitreous humor:
text: vitreous humor
description: A transparent, semigelatinous substance that fills the cavity behind
the crystalline lens of the eye and in front of the retina.
meaning: UBERON:0001797
whole blood:
text: whole blood
description: An achromatic cell of the myeloid or lymphoid lineages capable of
ameboid movement, found in blood or other tissue.
meaning: CL:0000738