Class: DissociatedCellSample
A collection of dissociated cells or nuclei derived from dissociation of a tissue sample.
URI: bican:DissociatedCellSample
classDiagram
class DissociatedCellSample
click DissociatedCellSample href "../DissociatedCellSample"
ProvEntity <|-- DissociatedCellSample
click ProvEntity href "../ProvEntity"
MaterialSample <|-- DissociatedCellSample
click MaterialSample href "../MaterialSample"
DissociatedCellSample : category
DissociatedCellSample : cell_prep_type
DissociatedCellSample --> "0..1" DissociatedCellSampleCellPrepType : cell_prep_type
click DissociatedCellSampleCellPrepType href "../DissociatedCellSampleCellPrepType"
DissociatedCellSample : cell_source_oligo_name
DissociatedCellSample --> "0..1" DissociatedCellSampleCellLabelBarcode : cell_source_oligo_name
click DissociatedCellSampleCellLabelBarcode href "../DissociatedCellSampleCellLabelBarcode"
DissociatedCellSample : deprecated
DissociatedCellSample : description
DissociatedCellSample : full_name
DissociatedCellSample : has_attribute
DissociatedCellSample --> "*" Attribute : has_attribute
click Attribute href "../Attribute"
DissociatedCellSample : id
DissociatedCellSample : iri
DissociatedCellSample : name
DissociatedCellSample : provided_by
DissociatedCellSample : synonym
DissociatedCellSample : type
DissociatedCellSample : was_derived_from
DissociatedCellSample --> "*" TissueSample : was_derived_from
click TissueSample href "../TissueSample"
DissociatedCellSample : was_generated_by
DissociatedCellSample --> "0..1" CellDissociation : was_generated_by
click CellDissociation href "../CellDissociation"
DissociatedCellSample : xref
Inheritance
- Entity
- NamedThing
- PhysicalEntity [ PhysicalEssence]
- MaterialSample [ SubjectOfInvestigation]
- DissociatedCellSample [ ProvEntity]
- MaterialSample [ SubjectOfInvestigation]
- PhysicalEntity [ PhysicalEssence]
- NamedThing
Slots
Name | Cardinality and Range | Description | Inheritance |
---|---|---|---|
was_generated_by | 0..1 CellDissociation |
The cell dissociation process from which the dissociated cell sample was gene... | direct |
was_derived_from | * TissueSample |
The input tissue sample(s) from which dissociated cell sample was derived fro... | direct |
name | 0..1 LabelType |
Name of a collection of dissociated cells or nuclei derived from dissociation... | direct |
cell_prep_type | 0..1 DissociatedCellSampleCellPrepType |
The type of cell preparation | direct |
cell_source_oligo_name | 0..1 DissociatedCellSampleCellLabelBarcode |
Name of cell source oligo used in cell plexing | direct |
id | 1 String |
A unique identifier for an entity | Entity, MaterialSample, NamedThing, PhysicalEntity |
iri | 0..1 IriType |
An IRI for an entity | Entity, MaterialSample, NamedThing, PhysicalEntity |
category | * Curie |
Name of the high level ontology class in which this entity is categorized | Entity, MaterialSample, NamedThing, PhysicalEntity |
type | * String |
Entity, MaterialSample, NamedThing, PhysicalEntity | |
description | 0..1 NarrativeText |
a human-readable description of an entity | Entity, MaterialSample, NamedThing, PhysicalEntity |
has_attribute | * Attribute |
connects any entity to an attribute | Entity, MaterialSample, NamedThing, PhysicalEntity |
deprecated | 0..1 Boolean |
A boolean flag indicating that an entity is no longer considered current or v... | Entity, MaterialSample, NamedThing, PhysicalEntity |
provided_by | * String |
The value in this node property represents the knowledge provider that create... | MaterialSample, NamedThing, PhysicalEntity |
xref | * Uriorcurie |
A database cross reference or alternative identifier for a NamedThing or edge... | MaterialSample, NamedThing, PhysicalEntity |
full_name | 0..1 LabelType |
a long-form human readable name for a thing | MaterialSample, NamedThing, PhysicalEntity |
synonym | * LabelType |
Alternate human-readable names for a thing | MaterialSample, NamedThing, PhysicalEntity |
Usages
used by | used in | type | used |
---|---|---|---|
EnrichedCellSample | was_derived_from | exactly_one_of[range] | DissociatedCellSample |
BarcodedCellSample | was_derived_from | exactly_one_of[range] | DissociatedCellSample |
CellEnrichment | used | range | DissociatedCellSample |
CellBarcoding | used | exactly_one_of[range] | DissociatedCellSample |
Identifier and Mapping Information
Schema Source
- from schema: https://identifiers.org/brain-bican/library-generation-schema
Mappings
Mapping Type | Mapped Value |
---|---|
self | bican:DissociatedCellSample |
native | bican:DissociatedCellSample |
exact | NIMP:Dissociated%20Cell%20Sample |
LinkML Source
Direct
name: DissociatedCellSample
description: A collection of dissociated cells or nuclei derived from dissociation
of a tissue sample.
in_subset:
- bican
- library_generation
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:Dissociated%20Cell%20Sample
is_a: material sample
mixins:
- ProvEntity
slots:
- was_generated_by
- was_derived_from
- name
slot_usage:
was_generated_by:
name: was_generated_by
description: The cell dissociation process from which the dissociated cell sample
was generated by.
domain_of:
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryPool
- DissectionRoiPolygon
- ProvEntity
range: CellDissociation
was_derived_from:
name: was_derived_from
description: The input tissue sample(s) from which dissociated cell sample was
derived from.
exact_mappings:
- NIMP:has_parent
domain_of:
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DigitalAsset
- ProvEntity
range: TissueSample
multivalued: true
name:
name: name
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_local_name
description: Name of a collection of dissociated cells or nuclei derived from
dissociation of a tissue sample.
exact_mappings:
- NIMP:PD-RQRWHS40
slot_uri: bican:65e2c7da-9eb4-45b2-8ccb-d69ef9785ee2
domain_of:
- Donor
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DissectionRoiPolygon
- entity
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- macromolecular machine mixin
- gene or gene product
- gene
- genome
attributes:
cell_prep_type:
name: cell_prep_type
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_cell_prep_type
description: 'The type of cell preparation. For example: Cells, Nuclei. This is
a property of dissociated_cell_sample.'
in_subset:
- analysis
- tracking
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:PD-RELLGO26
rank: 1000
slot_uri: bican:baae4ac3-f959-4594-b943-3a82ec19bd34
alias: dissociated cell sample cell prep type
domain_of:
- DissociatedCellSample
range: dissociated_cell_sample_cell_prep_type
cell_source_oligo_name:
name: cell_source_oligo_name
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_cell_label_barcode
description: Name of cell source oligo used in cell plexing. The oligo molecularly
tags all the cells in the dissociated cell sample and allows separate dissociated
cell samples to be combined downstream in the barcoded cell sample. The oligo
name is associated with a sequence in a lookup table. This sequence will be
needed during alignment to associate reads with the parent source dissociated
cell sample.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:PD-CFCFPS27
rank: 1000
slot_uri: bican:184abbaf-baff-4b5f-b51e-dd38de6006af
alias: dissociated cell oligo tag name
domain_of:
- DissociatedCellSample
- EnrichedCellSample
range: dissociated_cell_sample_cell_label_barcode
Induced
name: DissociatedCellSample
description: A collection of dissociated cells or nuclei derived from dissociation
of a tissue sample.
in_subset:
- bican
- library_generation
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:Dissociated%20Cell%20Sample
is_a: material sample
mixins:
- ProvEntity
slot_usage:
was_generated_by:
name: was_generated_by
description: The cell dissociation process from which the dissociated cell sample
was generated by.
domain_of:
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryPool
- DissectionRoiPolygon
- ProvEntity
range: CellDissociation
was_derived_from:
name: was_derived_from
description: The input tissue sample(s) from which dissociated cell sample was
derived from.
exact_mappings:
- NIMP:has_parent
domain_of:
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DigitalAsset
- ProvEntity
range: TissueSample
multivalued: true
name:
name: name
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_local_name
description: Name of a collection of dissociated cells or nuclei derived from
dissociation of a tissue sample.
exact_mappings:
- NIMP:PD-RQRWHS40
slot_uri: bican:65e2c7da-9eb4-45b2-8ccb-d69ef9785ee2
domain_of:
- Donor
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DissectionRoiPolygon
- entity
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- macromolecular machine mixin
- gene or gene product
- gene
- genome
attributes:
cell_prep_type:
name: cell_prep_type
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_cell_prep_type
description: 'The type of cell preparation. For example: Cells, Nuclei. This is
a property of dissociated_cell_sample.'
in_subset:
- analysis
- tracking
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:PD-RELLGO26
rank: 1000
slot_uri: bican:baae4ac3-f959-4594-b943-3a82ec19bd34
alias: dissociated cell sample cell prep type
owner: DissociatedCellSample
domain_of:
- DissociatedCellSample
range: dissociated_cell_sample_cell_prep_type
cell_source_oligo_name:
name: cell_source_oligo_name
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_cell_label_barcode
description: Name of cell source oligo used in cell plexing. The oligo molecularly
tags all the cells in the dissociated cell sample and allows separate dissociated
cell samples to be combined downstream in the barcoded cell sample. The oligo
name is associated with a sequence in a lookup table. This sequence will be
needed during alignment to associate reads with the parent source dissociated
cell sample.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:PD-CFCFPS27
rank: 1000
slot_uri: bican:184abbaf-baff-4b5f-b51e-dd38de6006af
alias: dissociated cell oligo tag name
owner: DissociatedCellSample
domain_of:
- DissociatedCellSample
- EnrichedCellSample
range: dissociated_cell_sample_cell_label_barcode
was_generated_by:
name: was_generated_by
description: The cell dissociation process from which the dissociated cell sample
was generated by.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
rank: 1000
slot_uri: prov:wasGeneratedBy
alias: was_generated_by
owner: DissociatedCellSample
domain_of:
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryPool
- DissectionRoiPolygon
- ProvEntity
range: CellDissociation
was_derived_from:
name: was_derived_from
description: The input tissue sample(s) from which dissociated cell sample was
derived from.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:has_parent
rank: 1000
slot_uri: prov:wasDerivedFrom
alias: was_derived_from
owner: DissociatedCellSample
domain_of:
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DigitalAsset
- ProvEntity
range: TissueSample
multivalued: true
name:
name: name
definition_uri: https://w3id.org/biolink/vocab/name
local_names:
NIMP:
local_name_source: NIMP
local_name_value: dissociated_cell_sample_local_name
description: Name of a collection of dissociated cells or nuclei derived from
dissociation of a tissue sample.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- NIMP:PD-RQRWHS40
rank: 1000
domain: entity
slot_uri: bican:65e2c7da-9eb4-45b2-8ccb-d69ef9785ee2
alias: name
owner: DissociatedCellSample
domain_of:
- Donor
- BrainSlab
- TissueSample
- DissociatedCellSample
- EnrichedCellSample
- BarcodedCellSample
- AmplifiedCdna
- Library
- LibraryAliquot
- LibraryPool
- DissectionRoiPolygon
- entity
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- macromolecular machine mixin
- gene or gene product
- gene
- genome
range: label type
id:
name: id
definition_uri: https://w3id.org/biolink/vocab/id
description: A unique identifier for an entity. Must be either a CURIE shorthand
for a URI or a complete URI
in_subset:
- translator_minimal
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- AGRKB:primaryId
- gff3:ID
- gpi:DB_Object_ID
rank: 1000
domain: entity
slot_uri: biolink:id
identifier: true
alias: id
owner: DissociatedCellSample
domain_of:
- ontology class
- entity
- attribute
- named thing
- taxonomic rank
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: string
required: true
iri:
name: iri
definition_uri: https://w3id.org/biolink/vocab/iri
description: An IRI for an entity. This is determined by the id using expansion
rules.
in_subset:
- translator_minimal
- samples
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- WIKIDATA_PROPERTY:P854
rank: 1000
slot_uri: biolink:iri
alias: iri
owner: DissociatedCellSample
domain_of:
- attribute
- entity
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: iri type
category:
name: category
definition_uri: https://w3id.org/biolink/vocab/category
description: 'Name of the high level ontology class in which this entity is categorized.
Corresponds to the label for the biolink entity type class. In a neo4j database
this MAY correspond to the neo4j label tag. In an RDF database it should be
a biolink model class URI. This field is multi-valued. It should include values
for ancestors of the biolink class; for example, a protein such as Shh would
have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`.
In an RDF database, nodes will typically have an rdf:type triples. This can
be to the most specific biolink class, or potentially to a class more specific
than something in biolink. For example, a sequence feature `f` may have a rdf:type
assertion to a SO class such as TF_binding_site, which is more specific than
anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity,
biolink:NamedThing}. NOTE: The category slot was modified to have a curie range
and a pattern for bican categories.'
in_subset:
- translator_minimal
from_schema: https://identifiers.org/brain-bican/library-generation-schema
rank: 1000
is_a: type
domain: entity
slot_uri: biolink:category
designates_type: true
alias: category
owner: DissociatedCellSample
domain_of:
- entity
- attribute
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
is_class_field: true
range: curie
multivalued: true
pattern: ^bican:[A-Z][A-Za-z]+$
type:
name: type
definition_uri: https://w3id.org/biolink/vocab/type
from_schema: https://identifiers.org/brain-bican/library-generation-schema
mappings:
- rdf:type
exact_mappings:
- gff3:type
- gpi:DB_Object_Type
rank: 1000
domain: entity
slot_uri: rdf:type
alias: type
owner: DissociatedCellSample
domain_of:
- entity
- attribute
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: string
multivalued: true
description:
name: description
definition_uri: https://w3id.org/biolink/vocab/description
description: a human-readable description of an entity
in_subset:
- translator_minimal
from_schema: https://identifiers.org/brain-bican/library-generation-schema
aliases:
- definition
mappings:
- dct:description
exact_mappings:
- IAO:0000115
- skos:definitions
narrow_mappings:
- gff3:Description
rank: 1000
slot_uri: dct:description
alias: description
owner: DissociatedCellSample
domain_of:
- entity
- attribute
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: narrative text
has attribute:
name: has attribute
definition_uri: https://w3id.org/biolink/vocab/has_attribute
description: connects any entity to an attribute
in_subset:
- samples
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- SIO:000008
close_mappings:
- OBI:0001927
narrow_mappings:
- OBAN:association_has_subject_property
- OBAN:association_has_object_property
- CPT:has_possibly_included_panel_element
- DRUGBANK:category
- EFO:is_executed_in
- HANCESTRO:0301
- LOINC:has_action_guidance
- LOINC:has_adjustment
- LOINC:has_aggregation_view
- LOINC:has_approach_guidance
- LOINC:has_divisor
- LOINC:has_exam
- LOINC:has_method
- LOINC:has_modality_subtype
- LOINC:has_object_guidance
- LOINC:has_scale
- LOINC:has_suffix
- LOINC:has_time_aspect
- LOINC:has_time_modifier
- LOINC:has_timing_of
- NCIT:R88
- NCIT:eo_disease_has_property_or_attribute
- NCIT:has_data_element
- NCIT:has_pharmaceutical_administration_method
- NCIT:has_pharmaceutical_basic_dose_form
- NCIT:has_pharmaceutical_intended_site
- NCIT:has_pharmaceutical_release_characteristics
- NCIT:has_pharmaceutical_state_of_matter
- NCIT:has_pharmaceutical_transformation
- NCIT:is_qualified_by
- NCIT:qualifier_applies_to
- NCIT:role_has_domain
- NCIT:role_has_range
- INO:0000154
- HANCESTRO:0308
- OMIM:has_inheritance_type
- orphanet:C016
- orphanet:C017
- RO:0000053
- RO:0000086
- RO:0000087
- SNOMED:has_access
- SNOMED:has_clinical_course
- SNOMED:has_count_of_base_of_active_ingredient
- SNOMED:has_dose_form_administration_method
- SNOMED:has_dose_form_release_characteristic
- SNOMED:has_dose_form_transformation
- SNOMED:has_finding_context
- SNOMED:has_finding_informer
- SNOMED:has_inherent_attribute
- SNOMED:has_intent
- SNOMED:has_interpretation
- SNOMED:has_laterality
- SNOMED:has_measurement_method
- SNOMED:has_method
- SNOMED:has_priority
- SNOMED:has_procedure_context
- SNOMED:has_process_duration
- SNOMED:has_property
- SNOMED:has_revision_status
- SNOMED:has_scale_type
- SNOMED:has_severity
- SNOMED:has_specimen
- SNOMED:has_state_of_matter
- SNOMED:has_subject_relationship_context
- SNOMED:has_surgical_approach
- SNOMED:has_technique
- SNOMED:has_temporal_context
- SNOMED:has_time_aspect
- SNOMED:has_units
- UMLS:has_structural_class
- UMLS:has_supported_concept_property
- UMLS:has_supported_concept_relationship
- UMLS:may_be_qualified_by
rank: 1000
domain: entity
slot_uri: biolink:has_attribute
alias: has_attribute
owner: DissociatedCellSample
domain_of:
- entity
- attribute
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: attribute
multivalued: true
deprecated:
name: deprecated
definition_uri: https://w3id.org/biolink/vocab/deprecated
description: A boolean flag indicating that an entity is no longer considered
current or valid.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
exact_mappings:
- oboInOwl:ObsoleteClass
rank: 1000
slot_uri: biolink:deprecated
alias: deprecated
owner: DissociatedCellSample
domain_of:
- entity
- attribute
- named thing
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: boolean
provided by:
name: provided by
definition_uri: https://w3id.org/biolink/vocab/provided_by
description: The value in this node property represents the knowledge provider
that created or assembled the node and all of its attributes. Used internally
to represent how a particular node made its way into a knowledge provider or
graph.
from_schema: https://identifiers.org/brain-bican/library-generation-schema
rank: 1000
is_a: node property
domain: named thing
slot_uri: biolink:provided_by
alias: provided_by
owner: DissociatedCellSample
domain_of:
- named thing
- attribute
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: string
multivalued: true
xref:
name: xref
definition_uri: https://w3id.org/biolink/vocab/xref
description: A database cross reference or alternative identifier for a NamedThing
or edge between two NamedThings. This property should point to a database record
or webpage that supports the existence of the edge, or gives more detail about
the edge. This property can be used on a node or edge to provide multiple URIs
or CURIE cross references.
in_subset:
- translator_minimal
from_schema: https://identifiers.org/brain-bican/library-generation-schema
aliases:
- dbxref
- Dbxref
- DbXref
- record_url
- source_record_urls
narrow_mappings:
- gff3:Dbxref
- gpi:DB_Xrefs
rank: 1000
domain: named thing
slot_uri: biolink:xref
alias: xref
owner: DissociatedCellSample
domain_of:
- named thing
- gene
- attribute
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- genome
range: uriorcurie
multivalued: true
full name:
name: full name
definition_uri: https://w3id.org/biolink/vocab/full_name
description: a long-form human readable name for a thing
from_schema: https://identifiers.org/brain-bican/library-generation-schema
rank: 1000
is_a: node property
domain: named thing
slot_uri: biolink:full_name
alias: full_name
owner: DissociatedCellSample
domain_of:
- named thing
- attribute
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: label type
synonym:
name: synonym
definition_uri: https://w3id.org/biolink/vocab/synonym
description: Alternate human-readable names for a thing
in_subset:
- translator_minimal
from_schema: https://identifiers.org/brain-bican/library-generation-schema
aliases:
- alias
narrow_mappings:
- skos:altLabel
- gff3:Alias
- AGRKB:synonyms
- gpi:DB_Object_Synonyms
- HANCESTRO:0330
- IAO:0000136
- RXNORM:has_tradename
rank: 1000
is_a: node property
domain: named thing
slot_uri: biolink:synonym
alias: synonym
owner: DissociatedCellSample
domain_of:
- named thing
- attribute
- organism taxon
- information content entity
- dataset
- physical entity
- activity
- procedure
- material sample
- biological entity
- gene
- genome
range: label type
multivalued: true