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CS202210140_99

DLCT6b_98 (CS202210140_99)

Hierarchy: CS202210140_474 > CS202210140_99

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_99


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L6b https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:7b6e7cc097 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 98
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1
Neuropeptide auto_annotation CBLN CCK CHGA CHGB IGF NAMPT NPY NUCB NXPH SCG UBL UCN VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L6b
Top three regions Cerebral cortex: 75.6%, Basal forebrain: 10.3%, Amygdala: 7.8%
Top three dissections Human MTG: 8.1%, Human FI: 8.1%, Human M1C: 5.9%
Top Enriched Genes ERG, CCN2, AC079949.3, SLC15A5, SCUBE1, AC002331.1, CDH24, DPP4, TNIP3, OLFML2B
Number of cells 4953.0
DoubletFinder score 0.041612111
Total UMI 28058.69958
Fraction unspliced 0.726186145
Fraction mitochondrial 0.007155651
H19.30.002 1567.0
H19.30.001 2052.0
H18.30.002 1148.0
H18.30.001 186.0
Fraction cells from top donor 0.414294367
Number of donors 4.0
subcluster_id None