CS202210140_428
MSN_427 (CS202210140_428)
Hierarchy: CS202210140_481 > CS202210140_428
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_428
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons FOXP1, DRD1 are known markers OTOF is a good marker in the human data, previously described as an eccentric MSN marker RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 427 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CART CCK CHGA CHGB NAMPT NUCB NXPH SCG SST TAC UBL VGF proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Amygdala: 56.6%, Hypothalamus: 19.3%, Thalamus: 14.0% |
| Top three dissections | Human BNST: 46.5%, Human ANC: 13.2%, Human HTHpo: 9.9% |
| Top Enriched Genes | AC022433.1, ISL1, AC010478.1, SCML4, GPR101, GABRG1, AC096759.1, TMEM215, AC025244.1, SCN5A |
| Number of cells | 3436.0 |
| DoubletFinder score | 0.06768342 |
| Total UMI | 23952.33586 |
| Fraction unspliced | 0.729289108 |
| Fraction mitochondrial | 0.025569627 |
| H19.30.002 | 535.0 |
| H19.30.001 | 1188.0 |
| H18.30.002 | 1705.0 |
| H18.30.001 | 8.0 |
| Fraction cells from top donor | 0.496216531 |
| Number of donors | 4.0 |
| subcluster_id | None |