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CS202210140_283

CGE_282 (CS202210140_283)

Hierarchy: CS202210140_486 > CS202210140_283

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_283


Labelset: Cluster (Rank: 1)

Parent Cell Set: CGE interneuron (CS202210140_486)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
Sncg https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:069c284831 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 282
Class auto_annotation NEUR
Neurotransmitter auto_annotation GABA
Neuropeptide auto_annotation CCK CHGA CHGB CRH IGF NAMPT NUCB PNOC SCG UBL proSAAS
Subtype auto_annotation None
Transferred MTG Label Sncg
Top three regions Cerebral cortex: 82.6%, Hippocampus: 11.9%, Amygdala: 2.2%
Top three dissections Human A32: 5.2%, Human MTG: 5.1%, Human M1C: 4.8%
Top Enriched Genes AC004862.1, AC091576.1, ADAM33, CXCL14, NDNF, AL139090.1, AL391832.4, AC073316.1, ARHGAP36, AC068633.1
Number of cells 10065.0
DoubletFinder score 0.022418843
Total UMI 11794.50094
Fraction unspliced 0.687094575
Fraction mitochondrial 0.007963189
H19.30.002 3030.0
H19.30.001 3864.0
H18.30.002 3070.0
H18.30.001 101.0
Fraction cells from top donor 0.38390462
Number of donors 4.0
subcluster_id None