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CS202210140_279

CGE_278 (CS202210140_279)

Hierarchy: CS202210140_486 > CS202210140_279

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_279


Labelset: Cluster (Rank: 1)

Parent Cell Set: CGE interneuron (CS202210140_486)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
Pax6 https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:ae541c9995 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 278
Class auto_annotation NEUR
Neurotransmitter auto_annotation GABA VGLUT3
Neuropeptide auto_annotation CCK CHGA CHGB CRH IGF NAMPT NPW NUCB NXPH PNOC SCG SST UBL proSAAS
Subtype auto_annotation None
Transferred MTG Label Pax6
Top three regions Cerebral cortex: 78.0%, Amygdala: 10.4%, Hippocampus: 8.1%
Top three dissections Human MEC: 5.9%, Human LEC: 4.8%, Human M1C: 4.7%
Top Enriched Genes SP8, CXCL14, DDR2, AC006305.1, AC005064.1, RELN, ABCB5, GRPR, AC092819.3, NDNF
Number of cells 7177.0
DoubletFinder score 0.040213577
Total UMI 15390.37188
Fraction unspliced 0.655600556
Fraction mitochondrial 0.011946499
H19.30.002 2298.0
H19.30.001 2635.0
H18.30.002 2168.0
H18.30.001 76.0
Fraction cells from top donor 0.367145047
Number of donors 4.0
subcluster_id None