CS202210140_276
LLC_275 (CS202210140_276)
Hierarchy: CS202210140_485 > CS202210140_276
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_276
Labelset: Cluster (Rank: 1)
Parent Cell Set: LAMP5-LHX6 and Chandelier (CS202210140_485)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Lamp5 Lhx6 | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c199218811 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 275 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB CORT IGF NAMPT NPPC NUCB NXPH PTHLH SCG UBL UCN proSAAS |
| Subtype auto_annotation | INT-LAMP5-LHX6 |
| Transferred MTG Label | Lamp5 Lhx6 |
| Top three regions | Cerebral cortex: 66.0%, Amygdala: 16.5%, Basal forebrain: 9.9% |
| Top three dissections | Human Cla: 7.5%, Human MEC: 6.9%, Human MTG: 5.9% |
| Top Enriched Genes | LINC01344, SFRP1, HAPLN1, PDGFD, EYA4, ADGRG6, ANO1, AC137770.1, AP002989.1, CRABP1 |
| Number of cells | 2174.0 |
| DoubletFinder score | 0.01905912 |
| Total UMI | 17263.0598 |
| Fraction unspliced | 0.701216357 |
| Fraction mitochondrial | 0.008496642 |
| H19.30.002 | 770.0 |
| H19.30.001 | 718.0 |
| H18.30.002 | 589.0 |
| H18.30.001 | 97.0 |
| Fraction cells from top donor | 0.354185833 |
| Number of donors | 4.0 |
| subcluster_id | None |