CS202210140_275
LLC_274 (CS202210140_275)
Hierarchy: CS202210140_485 > CS202210140_275
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_275
Labelset: Cluster (Rank: 1)
Parent Cell Set: LAMP5-LHX6 and Chandelier (CS202210140_485)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Lamp5 Lhx6 | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c199218811 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 274 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB CORT IGF NAMPT NPPC NUCB NXPH SCG UBL UCN proSAAS |
| Subtype auto_annotation | INT-LAMP5-LHX6 |
| Transferred MTG Label | Lamp5 Lhx6 |
| Top three regions | Cerebral cortex: 84.6%, Basal forebrain: 5.9%, Hippocampus: 3.1% |
| Top three dissections | Human M1C: 11.7%, Human MTG: 7.6%, Human Cla: 4.8% |
| Top Enriched Genes | LINC01344, AC137770.1, SFRP1, AC132803.1, HAPLN1, EYA4, PDGFD, ANO1, AP002989.1, LINC00298 |
| Number of cells | 6373.0 |
| DoubletFinder score | 0.022103033 |
| Total UMI | 18240.66076 |
| Fraction unspliced | 0.696552741 |
| Fraction mitochondrial | 0.007520357 |
| H19.30.002 | 2240.0 |
| H19.30.001 | 2033.0 |
| H18.30.002 | 1749.0 |
| H18.30.001 | 351.0 |
| Fraction cells from top donor | 0.351482818 |
| Number of donors | 4.0 |
| subcluster_id | None |