CS202210140_271
LLC_270 (CS202210140_271)
Hierarchy: CS202210140_485 > CS202210140_271
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_271
Labelset: Cluster (Rank: 1)
Parent Cell Set: LAMP5-LHX6 and Chandelier (CS202210140_485)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Lamp5 Lhx6 | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c199218811 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 270 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB CORT IGF NAMPT NPPC NUCB NXPH PNOC SCG TAC UBL proSAAS |
| Subtype auto_annotation | INT-LAMP5-LHX6 |
| Transferred MTG Label | Lamp5 Lhx6 |
| Top three regions | Cerebral cortex: 86.2%, Hippocampus: 6.7%, Thalamus: 3.3% |
| Top three dissections | Human M1C: 12.3%, Human MTG: 5.2%, Human S1C: 4.5% |
| Top Enriched Genes | LINC01344, SFRP1, ANO1, EYA4, LINC00943, CA1, PDGFD, NOS1, CHRDL1, CDCA7 |
| Number of cells | 4751.0 |
| DoubletFinder score | 0.025105175 |
| Total UMI | 15133.86782 |
| Fraction unspliced | 0.670136912 |
| Fraction mitochondrial | 0.012126181 |
| H19.30.002 | 1735.0 |
| H19.30.001 | 1504.0 |
| H18.30.002 | 1330.0 |
| H18.30.001 | 182.0 |
| Fraction cells from top donor | 0.365186277 |
| Number of donors | 4.0 |
| subcluster_id | None |