CS202210140_269
LLC_268 (CS202210140_269)
Hierarchy: CS202210140_485 > CS202210140_269
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_269
Labelset: Cluster (Rank: 1)
Parent Cell Set: LAMP5-LHX6 and Chandelier (CS202210140_485)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Lamp5 Lhx6 | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c199218811 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 268 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB CORT IGF NAMPT NPPC NUCB NXPH SCG SST TAC UBL VGF proSAAS |
| Subtype auto_annotation | INT-LAMP5-LHX6 |
| Transferred MTG Label | Lamp5 Lhx6 |
| Top three regions | Hippocampus: 95.5%, Cerebral cortex: 2.4%, Amygdala: 1.1% |
| Top three dissections | Human CA1U-CA2U-CA3U: 17.8%, Human CA3R: 17.6%, Human CA4C-DGC: 13.9% |
| Top Enriched Genes | CHRDL1, AL136456.1, EYA4, HAPLN1, LINC01344, CHST9, ANO1, TACR1, GRPR, NPPC |
| Number of cells | 3843.0 |
| DoubletFinder score | 0.027674376 |
| Total UMI | 22371.81056 |
| Fraction unspliced | 0.676160459 |
| Fraction mitochondrial | 0.008017228 |
| H19.30.002 | 1167.0 |
| H19.30.001 | 1179.0 |
| H18.30.002 | 1442.0 |
| H18.30.001 | 55.0 |
| Fraction cells from top donor | 0.375227687 |
| Number of donors | 4.0 |
| subcluster_id | None |