CS202210140_267
LLC_266 (CS202210140_267)
Hierarchy: CS202210140_485 > CS202210140_267
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_267
Labelset: Cluster (Rank: 1)
Parent Cell Set: LAMP5-LHX6 and Chandelier (CS202210140_485)
Cell Ontology Term: chandelier cell (CL:4023083)
Rationale: UNC5B, RORA, TRPS1, and NFIB from Bakken et. al 2021 motor cortex paper Note that these genes are also expressed in LAMP5-LHX6 cells. Added FOXG1 to limit this annotation to the telencephalon, and GAD1 to limit to GABAergic cells. ChC cells in our data did not express GAD2. Add CA8 based on the human data. Removed PVALB, some chandelier cells in our human data are PVALB negative
| Marker Genes |
|---|
| FOXG1 |
| GAD1 |
| UNC5B |
| RORA |
| TRPS1 |
| NFIB |
| CA8 |
| PLEKHH2 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 266 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB CRH IGF NAMPT NPPC NUCB NXPH PTHLH SCG SPX TAC UBL proSAAS |
| Subtype auto_annotation | CHAND |
| Transferred MTG Label | None |
| Top three regions | Amygdala: 42.8%, Hippocampus: 27.1%, Cerebral cortex: 25.1% |
| Top three dissections | Human CMN: 12.5%, Human BL: 8.8%, Human La: 8.4% |
| Top Enriched Genes | IL18R1, C1QL1, COL15A1, IBSP, LINC01837, CPED1, LINC00943, GRIN2C, LHX6, PTHLH |
| Number of cells | 3566.0 |
| DoubletFinder score | 0.025416841 |
| Total UMI | 18470.54964 |
| Fraction unspliced | 0.694616685 |
| Fraction mitochondrial | 0.008218698 |
| H19.30.002 | 1259.0 |
| H19.30.001 | 1260.0 |
| H18.30.002 | 1043.0 |
| H18.30.001 | 4.0 |
| Fraction cells from top donor | 0.353337072 |
| Number of donors | 4.0 |
| subcluster_id | None |