CS202210140_264
MGE_263 (CS202210140_264)
Hierarchy: CS202210140_484 > CS202210140_264
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_264
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Pvalb | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:5bcef2988c | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 263 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGA CHGB IGF NAMPT NPPC NUCB NXPH PNOC TAC UBL proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Pvalb |
| Top three regions | Cerebral cortex: 98.5%, Basal forebrain: 0.6%, Hippocampus: 0.4% |
| Top three dissections | Human M1C: 18.6%, Human A29-A30: 10.6%, Human V1C: 9.3% |
| Top Enriched Genes | LRRC38, OSTN, SULF1, TCIM, PVALB, ADAMTS17, RNF144B, AC118942.1, PRDM1, AL096865.1 |
| Number of cells | 6587.0 |
| DoubletFinder score | 0.011758818 |
| Total UMI | 17773.24488 |
| Fraction unspliced | 0.690364029 |
| Fraction mitochondrial | 0.006563263 |
| H19.30.002 | 2114.0 |
| H19.30.001 | 1940.0 |
| H18.30.002 | 2075.0 |
| H18.30.001 | 458.0 |
| Fraction cells from top donor | 0.320935175 |
| Number of donors | 4.0 |
| subcluster_id | None |