CS202210140_256
MGE_255 (CS202210140_256)
Hierarchy: CS202210140_484 > CS202210140_256
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_256
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Pvalb | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:5bcef2988c | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 255 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB CORT IGF NAMPT NPPC NUCB NXPH PNOC SCG TAC UBL VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Pvalb |
| Top three regions | Cerebral cortex: 67.2%, Amygdala: 13.0%, Hippocampus: 12.1% |
| Top three dissections | Human M1C: 5.6%, Human CEN: 5.0%, Human MTG: 4.3% |
| Top Enriched Genes | AC046195.2, WNT16, GLP1R, HGF, AL138899.1, MYBPC1, TRDN, LINC01885, AC046195.1, AC006364.1 |
| Number of cells | 3341.0 |
| DoubletFinder score | 0.033927258 |
| Total UMI | 19759.37534 |
| Fraction unspliced | 0.707349716 |
| Fraction mitochondrial | 0.006850231 |
| H19.30.002 | 1074.0 |
| H19.30.001 | 1445.0 |
| H18.30.002 | 718.0 |
| H18.30.001 | 104.0 |
| Fraction cells from top donor | 0.432505238 |
| Number of donors | 4.0 |
| subcluster_id | None |