CS202210140_252
MGE_251 (CS202210140_252)
Hierarchy: CS202210140_484 > CS202210140_252
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_252
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Sst | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:8fa477a378 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 251 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB CORT IGF NAMPT NMU NUCB NXPH PNOC SCG SST UBL VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Sst |
| Top three regions | Cerebral cortex: 94.0%, Hippocampus: 2.5%, Basal forebrain: 2.4% |
| Top three dissections | Human MTG: 6.6%, Human A29-A30: 5.6%, Human M1C: 4.6% |
| Top Enriched Genes | EDNRA, NMU, MAFB, CYP26A1, PNOC, PDCL2, KCNJ5, SST, TRBC2, ADGRG6 |
| Number of cells | 16688.0 |
| DoubletFinder score | 0.013882331 |
| Total UMI | 10511.36206 |
| Fraction unspliced | 0.693474103 |
| Fraction mitochondrial | 0.007225574 |
| H19.30.002 | 5283.0 |
| H19.30.001 | 5680.0 |
| H18.30.002 | 5370.0 |
| H18.30.001 | 355.0 |
| Fraction cells from top donor | 0.340364334 |
| Number of donors | 4.0 |
| subcluster_id | None |