CS202210140_251
MGE_250 (CS202210140_251)
Hierarchy: CS202210140_484 > CS202210140_251
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_251
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Sst | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:8fa477a378 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 250 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB CORT IGF NAMPT NMU NUCB NXPH PNOC SCG SST TAC UBL VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Sst |
| Top three regions | Cerebral cortex: 92.5%, Hippocampus: 2.4%, Basal forebrain: 2.2% |
| Top three dissections | Human MEC: 7.1%, Human M1C: 7.0%, Human MTG: 5.6% |
| Top Enriched Genes | PROM1, NMU, ADGRG6, AC022905.1, KCNJ5, MCUB, PAWR, SST, SCARA5, AC113347.4 |
| Number of cells | 16604.0 |
| DoubletFinder score | 0.021382996 |
| Total UMI | 13912.80896 |
| Fraction unspliced | 0.746955428 |
| Fraction mitochondrial | 0.004686223 |
| H19.30.002 | 4945.0 |
| H19.30.001 | 5180.0 |
| H18.30.002 | 6025.0 |
| H18.30.001 | 454.0 |
| Fraction cells from top donor | 0.36286437 |
| Number of donors | 4.0 |
| subcluster_id | None |