CS202210140_248
MGE_247 (CS202210140_248)
Hierarchy: CS202210140_484 > CS202210140_248
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_248
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Sst | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:8fa477a378 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 247 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB CORT IGF NAMPT NMU NPY NUCB NXPH SCG SST TAC UBL VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Sst |
| Top three regions | Hippocampus: 91.0%, Amygdala: 4.8%, Cerebral cortex: 3.4% |
| Top three dissections | Human CA1C-CA3C: 20.3%, Human CA1U-CA2U-CA3U: 19.1%, Human CA1: 16.6% |
| Top Enriched Genes | AC022133.2, AC022126.1, AL450345.2, KCNJ5, TNFSF15, LINC02624, MYHAS, ZAP70, LINC02192, FAM89A |
| Number of cells | 1110.0 |
| DoubletFinder score | 0.050824169 |
| Total UMI | 28003.45766 |
| Fraction unspliced | 0.723414711 |
| Fraction mitochondrial | 0.006162278 |
| H19.30.002 | 351.0 |
| H19.30.001 | 330.0 |
| H18.30.002 | 404.0 |
| H18.30.001 | 25.0 |
| Fraction cells from top donor | 0.363963964 |
| Number of donors | 4.0 |
| subcluster_id | None |