CS202210140_243
MGE_242 (CS202210140_243)
Hierarchy: CS202210140_484 > CS202210140_243
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_243
Labelset: Cluster (Rank: 1)
Parent Cell Set: MGE interneuron (CS202210140_484)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| Sst | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:8fa477a378 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 242 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | None |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB IGF NMU NUCB NXPH PENK PNOC SCG SST TAC proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | Sst |
| Top three regions | Cerebral cortex: 90.8%, Hippocampus: 4.6%, Basal forebrain: 1.8% |
| Top three dissections | Human M1C: 6.8%, Human MTG: 6.4%, Human A32: 5.4% |
| Top Enriched Genes | AC022905.1, AC113347.4, MCUB, ELFN1, DCN, FBN2, SLC27A6, TNFSF15, SST, LINC02397 |
| Number of cells | 15796.0 |
| DoubletFinder score | 0.017850097 |
| Total UMI | 9370.534312 |
| Fraction unspliced | 0.70051165 |
| Fraction mitochondrial | 0.012500008 |
| H19.30.002 | 5310.0 |
| H19.30.001 | 4467.0 |
| H18.30.002 | 5710.0 |
| H18.30.001 | 309.0 |
| Fraction cells from top donor | 0.36148392 |
| Number of donors | 4.0 |
| subcluster_id | None |