CS202210140_222
MSN_221 (CS202210140_222)
Hierarchy: CS202210140_481 > CS202210140_222
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_222
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: indirect pathway medium spiny neuron (CL:4023029)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| OTOF |
| DRD2 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 221 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CHGA CHGB NAMPT NUCB PENK SCG TAC UBL VGF proSAAS |
| Subtype auto_annotation | MSN-D2 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 78.8%, Amygdala: 9.0%, Cerebral cortex: 6.5% |
| Top three dissections | Human SI: 19.8%, Human Pu: 16.4%, Human NAC: 15.6% |
| Top Enriched Genes | AC048352.1, GPR6, LINC01305, DRD2, AC005482.1, RDH10, SIX3, LOXHD1, AC023905.1, AL392086.1 |
| Number of cells | 2571.0 |
| DoubletFinder score | 0.036791986 |
| Total UMI | 31331.32944 |
| Fraction unspliced | 0.720242848 |
| Fraction mitochondrial | 0.005946738 |
| H19.30.002 | 699.0 |
| H19.30.001 | 825.0 |
| H18.30.002 | 1047.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.407234539 |
| Number of donors | 3.0 |
| subcluster_id | None |