CS202210140_220
MSN_219 (CS202210140_220)
Hierarchy: CS202210140_481 > CS202210140_220
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_220
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 219 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CHGA CHGB NAMPT NUCB NXPH PDYN PENK SCG TAC UBL VGF VIP proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Amygdala: 33.2%, Basal forebrain: 32.8%, Hypothalamus: 18.6% |
| Top three dissections | Human SI: 31.0%, Human BNST: 23.2%, Human HTHpo: 13.6% |
| Top Enriched Genes | ISL1, NPNT, AC010478.1, LINC02462, PROK2, AC015631.1, DRD3, AC022433.1, NMBR, LINC01951 |
| Number of cells | 8342.0 |
| DoubletFinder score | 0.031139352 |
| Total UMI | 16908.75474 |
| Fraction unspliced | 0.716584247 |
| Fraction mitochondrial | 0.013514562 |
| H19.30.002 | 1775.0 |
| H19.30.001 | 2415.0 |
| H18.30.002 | 4152.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.497722369 |
| Number of donors | 3.0 |
| subcluster_id | None |