CS202210140_218
MSN_217 (CS202210140_218)
Hierarchy: CS202210140_481 > CS202210140_218
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_218
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: indirect pathway medium spiny neuron (CL:4023029)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| OTOF |
| DRD2 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 217 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB PENK SCG UBL VGF proSAAS |
| Subtype auto_annotation | MSN-D2 |
| Transferred MTG Label | None |
| Top three regions | Amygdala: 69.5%, Basal forebrain: 15.7%, Hypothalamus: 7.4% |
| Top three dissections | Human CEN: 36.4%, Human BNST: 21.2%, Human SI: 12.3% |
| Top Enriched Genes | DCDC2C, PENK, AC015631.1, SIX3, P2RY1, LINC02462, LINC01305, CALCR, CACNG5, LINC01833 |
| Number of cells | 7260.0 |
| DoubletFinder score | 0.040983613 |
| Total UMI | 22575.25303 |
| Fraction unspliced | 0.754972116 |
| Fraction mitochondrial | 0.013556075 |
| H19.30.002 | 1428.0 |
| H19.30.001 | 1874.0 |
| H18.30.002 | 3954.0 |
| H18.30.001 | 4.0 |
| Fraction cells from top donor | 0.544628099 |
| Number of donors | 4.0 |
| subcluster_id | None |