CS202210140_217
MSN_216 (CS202210140_217)
Hierarchy: CS202210140_481 > CS202210140_217
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_217
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: indirect pathway medium spiny neuron (CL:4023029)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| OTOF |
| DRD2 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 216 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CCK CHGB NAMPT NUCB PENK SCG UBL VGF proSAAS |
| Subtype auto_annotation | MSN-D2 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 40.9%, Amygdala: 26.3%, Hypothalamus: 18.3% |
| Top three dissections | Human SI: 36.9%, Human BNST: 19.4%, Human HTHpo: 16.1% |
| Top Enriched Genes | DRD2, MYO3A, PENK, ADORA2A, LINC01833, GPR6, LINC02462, AL020994.2, P2RY1, SIX3 |
| Number of cells | 5720.0 |
| DoubletFinder score | 0.034240263 |
| Total UMI | 23286.28147 |
| Fraction unspliced | 0.753565541 |
| Fraction mitochondrial | 0.010296755 |
| H19.30.002 | 1457.0 |
| H19.30.001 | 1835.0 |
| H18.30.002 | 2428.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.424475524 |
| Number of donors | 3.0 |
| subcluster_id | None |