CS202210140_216
MSN_215 (CS202210140_216)
Hierarchy: CS202210140_481 > CS202210140_216
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_216
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 215 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGB NAMPT NUCB PDYN PENK SCG TAC UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 85.0%, Amygdala: 9.2%, Cerebral cortex: 3.6% |
| Top three dissections | Human NAC: 43.8%, Human GPe: 16.9%, Human BNST: 8.9% |
| Top Enriched Genes | LINC02137, AC090124.1, AC068875.1, DRD3, AC092604.1, AL049830.3, C6orf141, AL445584.2, AL020994.2, AC107208.1 |
| Number of cells | 16654.0 |
| DoubletFinder score | 0.028758071 |
| Total UMI | 30352.45833 |
| Fraction unspliced | 0.729332493 |
| Fraction mitochondrial | 0.004788471 |
| H19.30.002 | 4293.0 |
| H19.30.001 | 6034.0 |
| H18.30.002 | 6327.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.379908731 |
| Number of donors | 3.0 |
| subcluster_id | None |