CS202210140_215
MSN_214 (CS202210140_215)
Hierarchy: CS202210140_481 > CS202210140_215
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_215
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 214 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CCK CHGB NAMPT NUCB PDYN PENK SCG TAC UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 61.9%, Amygdala: 15.7%, Cerebral cortex: 13.3% |
| Top three dissections | Human SI: 37.9%, Human NAC: 15.7%, Human BNST: 14.8% |
| Top Enriched Genes | DRD3, AC010478.1, PDYN, AL020994.2, GPR101, AL359220.1, AC092604.1, MYO3A, DRD1, C6orf141 |
| Number of cells | 14016.0 |
| DoubletFinder score | 0.032771697 |
| Total UMI | 24653.14676 |
| Fraction unspliced | 0.74941152 |
| Fraction mitochondrial | 0.006404952 |
| H19.30.002 | 4120.0 |
| H19.30.001 | 4690.0 |
| H18.30.002 | 5206.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.371432648 |
| Number of donors | 3.0 |
| subcluster_id | None |