CS202210140_214
MSN_213 (CS202210140_214)
Hierarchy: CS202210140_481 > CS202210140_214
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_214
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: indirect pathway medium spiny neuron (CL:4023029)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| OTOF |
| DRD2 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 213 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CBLN CHGB NAMPT NUCB PENK SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D2 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 75.5%, Cerebral cortex: 12.2%, Amygdala: 9.4% |
| Top three dissections | Human SI: 30.9%, Human NAC: 26.6%, Human GPe: 14.4% |
| Top Enriched Genes | PENK, AC008786.1, GPR6, DRD3, DRD2, P2RY1, SCIN, AC092604.1, ENTHD1, AL020994.2 |
| Number of cells | 13450.0 |
| DoubletFinder score | 0.025054734 |
| Total UMI | 24934.53442 |
| Fraction unspliced | 0.736914668 |
| Fraction mitochondrial | 0.004374918 |
| H19.30.002 | 3803.0 |
| H19.30.001 | 5110.0 |
| H18.30.002 | 4537.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.379925651 |
| Number of donors | 3.0 |
| subcluster_id | None |