CS202210140_213
MSN_212 (CS202210140_213)
Hierarchy: CS202210140_481 > CS202210140_213
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_213
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: indirect pathway medium spiny neuron (CL:4023029)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| OTOF |
| DRD2 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 212 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CHGB NAMPT NUCB PENK SCG TAC UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D2 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 90.4%, Cerebral cortex: 3.6%, Amygdala: 3.6% |
| Top three dissections | Human CaB: 25.4%, Human Pu: 22.3%, Human NAC: 18.4% |
| Top Enriched Genes | PENK, AL139379.1, GPR6, DRD2, AL450332.1, ADORA2A, AC107208.1, GPR88, AC092979.1, LINC02137 |
| Number of cells | 6867.0 |
| DoubletFinder score | 0.030221854 |
| Total UMI | 28319.32809 |
| Fraction unspliced | 0.724593934 |
| Fraction mitochondrial | 0.004656523 |
| H19.30.002 | 2053.0 |
| H19.30.001 | 2422.0 |
| H18.30.002 | 2392.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.352701325 |
| Number of donors | 3.0 |
| subcluster_id | None |