CS202210140_212
MSN_211 (CS202210140_212)
Hierarchy: CS202210140_481 > CS202210140_212
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_212
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 211 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CHGB NAMPT NUCB PDYN PENK SCG TAC UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 85.7%, Amygdala: 6.3%, Cerebral cortex: 4.2% |
| Top three dissections | Human CaB: 26.7%, Human NAC: 18.8%, Human Pu: 17.8% |
| Top Enriched Genes | AL445584.2, AL450332.1, LINC02137, TH, CA12, AC138646.1, PDYN, AC107208.1, AL139379.1, MME |
| Number of cells | 9093.0 |
| DoubletFinder score | 0.03025003 |
| Total UMI | 30213.50621 |
| Fraction unspliced | 0.728273598 |
| Fraction mitochondrial | 0.004776795 |
| H19.30.002 | 2484.0 |
| H19.30.001 | 3640.0 |
| H18.30.002 | 2969.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.400307929 |
| Number of donors | 3.0 |
| subcluster_id | None |