CS202210140_211
MSN_210 (CS202210140_211)
Hierarchy: CS202210140_481 > CS202210140_211
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_211
Labelset: Cluster (Rank: 1)
Parent Cell Set: Medium spiny neuron (CS202210140_481)
Cell Ontology Term: direct pathway medium spiny neuron (CL:4023026)
Rationale: FOXG1 and GAD2 to restrict the annotation to inhibitory telencephalic neurons. FOXP1, DRD1 are canonical markers. OTOF is a good marker in the human data, previously described as an eccentric MSN marker. RGS9 and GPR88 from mouse auto-annotation
| Marker Genes |
|---|
| FOXG1 |
| SLC32A1 |
| FOXP1 |
| FOXP2 |
| OTOF |
| DRD1 |
| RGS9 |
| GPR88 |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 210 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | GABA |
| Neuropeptide auto_annotation | CHGB NAMPT NUCB PENK SCG TAC UBL UCN VGF proSAAS |
| Subtype auto_annotation | MSN-D1 |
| Transferred MTG Label | None |
| Top three regions | Basal forebrain: 97.9%, Thalamus: 1.9%, Hippocampus: 0.2% |
| Top three dissections | Human Pu: 80.1%, Human CaB: 12.7%, Human GPe: 4.5% |
| Top Enriched Genes | LINC02137, AL445584.2, AL450332.1, DDIT4L, PTPN7, LPL, AC092979.1, MME, PLEK, SLC25A24P1 |
| Number of cells | 10299.0 |
| DoubletFinder score | 0.031642177 |
| Total UMI | 29569.87746 |
| Fraction unspliced | 0.731589014 |
| Fraction mitochondrial | 0.004437782 |
| H19.30.002 | 2998.0 |
| H19.30.001 | 3308.0 |
| H18.30.002 | 3993.0 |
| H18.30.001 | 0.0 |
| Fraction cells from top donor | 0.387707544 |
| Number of donors | 3.0 |
| subcluster_id | None |