CS202210140_176
Amex_175 (CS202210140_176)
Hierarchy: CS202210140_478 > CS202210140_176
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_176
Labelset: Cluster (Rank: 1)
Parent Cell Set: Amygdala excitatory (CS202210140_478)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L2/3 IT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:58570ade17 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 175 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 VGLUT2 |
| Neuropeptide auto_annotation | ADCYAP CART CBLN CCK CHGA CHGB GRP NAMPT NTS NUCB PDYN SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L2/3 IT |
| Top three regions | Cerebral cortex: 91.3%, Hippocampus: 7.3%, Amygdala: 1.2% |
| Top three dissections | Human MEC: 82.6%, Human LEC: 8.2%, Human Sub: 6.4% |
| Top Enriched Genes | AL035446.2, LINC00383, AC009081.2, AL138694.1, AC116345.1, SMIM36, FBLN2, AC113137.1, AC009878.2, CARM1P1 |
| Number of cells | 8112.0 |
| DoubletFinder score | 0.025820615 |
| Total UMI | 48088.63881 |
| Fraction unspliced | 0.762570536 |
| Fraction mitochondrial | 0.001195634 |
| H19.30.002 | 1596.0 |
| H19.30.001 | 1810.0 |
| H18.30.002 | 4702.0 |
| H18.30.001 | 4.0 |
| Fraction cells from top donor | 0.579635108 |
| Number of donors | 4.0 |
| subcluster_id | None |