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CS202210140_153

DLIT_152 (CS202210140_153)

Hierarchy: CS202210140_477 > CS202210140_153

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_153


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L6 IT Car3 https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:bbbf984b37 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 152
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1 VGLUT2 VGLUT3
Neuropeptide auto_annotation CBLN CCK CHGA CHGB NAMPT NUCB PYY SCG UBL UCN VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L6 IT Car3
Top three regions Basal forebrain: 76.2%, Amygdala: 19.9%, Cerebral cortex: 3.8%
Top three dissections Human Cla: 70.7%, Human CEN: 17.6%, Human Pu: 5.6%
Top Enriched Genes AC012593.2, ANXA1, SMIM32, LINC01876, AC074099.1, LINC02505, AC112481.2, PLA2G4A, SMYD1, AL136119.1
Number of cells 6048.0
DoubletFinder score 0.039769845
Total UMI 38763.39683
Fraction unspliced 0.74330317
Fraction mitochondrial 0.00748168
H19.30.002 1962.0
H19.30.001 2105.0
H18.30.002 1921.0
H18.30.001 60.0
Fraction cells from top donor 0.348048942
Number of donors 4.0
subcluster_id None