CS202210140_151
DLIT_150 (CS202210140_151)
Hierarchy: CS202210140_477 > CS202210140_151
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_151
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6 IT Car3 | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:bbbf984b37 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 150 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 VGLUT2 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6 IT Car3 |
| Top three regions | Cerebral cortex: 95.3%, Hippocampus: 2.2%, Basal forebrain: 1.3% |
| Top three dissections | Human M1C: 11.9%, Human MTG: 7.3%, Human A23: 4.7% |
| Top Enriched Genes | SMYD1, OLFML2B, SMIM32, POSTN, THEMIS, AL136119.1, MCTP2, GAS2L3, AL356432.3, NTNG2 |
| Number of cells | 12307.0 |
| DoubletFinder score | 0.034325742 |
| Total UMI | 24651.3849 |
| Fraction unspliced | 0.724110223 |
| Fraction mitochondrial | 0.004142091 |
| H19.30.002 | 3834.0 |
| H19.30.001 | 3553.0 |
| H18.30.002 | 4341.0 |
| H18.30.001 | 579.0 |
| Fraction cells from top donor | 0.352726091 |
| Number of donors | 4.0 |
| subcluster_id | None |