CS202210140_149
DLIT_148 (CS202210140_149)
Hierarchy: CS202210140_477 > CS202210140_149
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_149
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6 IT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:d6ef7e7411 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 148 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6 IT |
| Top three regions | Cerebral cortex: 85.2%, Basal forebrain: 6.0%, Amygdala: 5.0% |
| Top three dissections | Human MTG: 7.7%, Human ACC: 7.4%, Human FI: 6.6% |
| Top Enriched Genes | LINC00343, AC011754.1, THEMIS, TMEM233, AL356432.3, AC092131.1, AC079163.2, AC004917.1, AC015943.1, SH2D1B |
| Number of cells | 16196.0 |
| DoubletFinder score | 0.030169356 |
| Total UMI | 36001.95345 |
| Fraction unspliced | 0.739723218 |
| Fraction mitochondrial | 0.003713576 |
| H19.30.002 | 5064.0 |
| H19.30.001 | 4918.0 |
| H18.30.002 | 5439.0 |
| H18.30.001 | 775.0 |
| Fraction cells from top donor | 0.33582366 |
| Number of donors | 4.0 |
| subcluster_id | None |