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CS202210140_145

DLIT_144 (CS202210140_145)

Hierarchy: CS202210140_477 > CS202210140_145

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_145


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L5 IT https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:c6694cb883 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 144
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1
Neuropeptide auto_annotation CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L5 IT
Top three regions Cerebral cortex: 96.2%, Basal forebrain: 1.4%, Amygdala: 1.2%
Top three dissections Human MTG: 13.0%, Human M1C: 10.4%, Human A43: 5.0%
Top Enriched Genes AC021134.1, AL033539.2, TRABD2A, AC079052.1, AL138927.1, LINC01680, AL158835.1, AC073091.1, AL445207.1, Z68323.1
Number of cells 27079.0
DoubletFinder score 0.031161775
Total UMI 30471.2311
Fraction unspliced 0.71327384
Fraction mitochondrial 0.005842368
H19.30.002 7697.0
H19.30.001 8213.0
H18.30.002 9885.0
H18.30.001 1284.0
Fraction cells from top donor 0.365043022
Number of donors 4.0
subcluster_id None