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CS202210140_144

DLIT_143 (CS202210140_144)

Hierarchy: CS202210140_477 > CS202210140_144

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_144


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L5 IT https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:c6694cb883 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 143
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1
Neuropeptide auto_annotation CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L5 IT
Top three regions Cerebral cortex: 89.0%, Basal forebrain: 4.2%, Amygdala: 4.2%
Top three dissections Human MEC: 14.2%, Human ACC: 10.5%, Human A38: 9.9%
Top Enriched Genes AC021134.1, Z68323.1, AL033539.2, AC079052.1, AC021134.2, LINC01821, TRABD2A, LINC01606, ADTRP, LINC01320
Number of cells 13468.0
DoubletFinder score 0.038692578
Total UMI 44976.77287
Fraction unspliced 0.755768804
Fraction mitochondrial 0.00344533
H19.30.002 3683.0
H19.30.001 4143.0
H18.30.002 5165.0
H18.30.001 477.0
Fraction cells from top donor 0.383501634
Number of donors 4.0
subcluster_id None