CS202210140_143
DLIT_142 (CS202210140_143)
Hierarchy: CS202210140_477 > CS202210140_143
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_143
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L5 IT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c6694cb883 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 142 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L5 IT |
| Top three regions | Cerebral cortex: 96.0%, Hippocampus: 1.3%, Basal forebrain: 1.2% |
| Top three dissections | Human M1C: 26.9%, Human MTG: 11.3%, Human S1C: 4.8% |
| Top Enriched Genes | AC099517.1, Z68323.1, ADTRP, AC060765.2, AC021594.2, AL022724.3, AL359636.2, AL391117.1, AC008127.1, ALPL |
| Number of cells | 14326.0 |
| DoubletFinder score | 0.061459576 |
| Total UMI | 41713.66446 |
| Fraction unspliced | 0.729988162 |
| Fraction mitochondrial | 0.005153202 |
| H19.30.002 | 3200.0 |
| H19.30.001 | 3844.0 |
| H18.30.002 | 5803.0 |
| H18.30.001 | 1479.0 |
| Fraction cells from top donor | 0.405067709 |
| Number of donors | 4.0 |
| subcluster_id | None |