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CS202210140_140

DLIT_139 (CS202210140_140)

Hierarchy: CS202210140_477 > CS202210140_140

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_140


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L5 IT https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:c6694cb883 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 139
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1 VGLUT2
Neuropeptide auto_annotation CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L5 IT
Top three regions Cerebral cortex: 95.2%, Basal forebrain: 1.9%, Hippocampus: 1.5%
Top three dissections Human MTG: 12.0%, Human M1C: 7.8%, Human A43: 4.4%
Top Enriched Genes AC016687.2, AC016687.3, AP003066.1, AL033539.2, AC099517.1, AC073578.2, Z68323.1, AC060765.2, AC021134.1, RCSD1
Number of cells 24657.0
DoubletFinder score 0.026565668
Total UMI 23385.0842
Fraction unspliced 0.689132591
Fraction mitochondrial 0.007590162
H19.30.002 6690.0
H19.30.001 7447.0
H18.30.002 9361.0
H18.30.001 1159.0
Fraction cells from top donor 0.379648781
Number of donors 4.0
subcluster_id None