CS202210140_138
DLIT_137 (CS202210140_138)
Hierarchy: CS202210140_477 > CS202210140_138
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_138
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer intratelencephalic (CS202210140_477)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L5 IT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:c6694cb883 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 137 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 VGLUT2 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB CRH NAMPT NUCB SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L5 IT |
| Top three regions | Cerebral cortex: 94.4%, Basal forebrain: 2.1%, Hippocampus: 1.9% |
| Top three dissections | Human MTG: 7.5%, Human A13: 5.6%, Human M1C: 4.6% |
| Top Enriched Genes | LINC02196, AC099517.1, AC079380.1, AC073578.2, ADGRL4, PKD2L1, AC021134.1, AL450352.1, TRIM22, ARHGAP15 |
| Number of cells | 17737.0 |
| DoubletFinder score | 0.033748944 |
| Total UMI | 24536.47601 |
| Fraction unspliced | 0.708154042 |
| Fraction mitochondrial | 0.005179249 |
| H19.30.002 | 5267.0 |
| H19.30.001 | 5364.0 |
| H18.30.002 | 6590.0 |
| H18.30.001 | 516.0 |
| Fraction cells from top donor | 0.371539719 |
| Number of donors | 4.0 |
| subcluster_id | None |