CS202210140_130
ULIT_129 (CS202210140_130)
Hierarchy: CS202210140_476 > CS202210140_130
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_130
Labelset: Cluster (Rank: 1)
Parent Cell Set: Upper-layer intratelencephalic (CS202210140_476)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L2/3 IT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:58570ade17 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 129 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 VGLUT2 |
| Neuropeptide auto_annotation | ADCYAP CART CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L2/3 IT |
| Top three regions | Cerebral cortex: 99.1%, Hippocampus: 0.4%, Basal forebrain: 0.4% |
| Top three dissections | Human MTG: 14.4%, Human A44-A45: 8.5%, Human A46: 6.7% |
| Top Enriched Genes | LINC02296, LINC00326, AC110014.1, AC016598.2, AJ009632.2, LINC01478, AC016598.1, AC008696.2, LINC00508, LINC00507 |
| Number of cells | 46343.0 |
| DoubletFinder score | 0.045085703 |
| Total UMI | 33171.36204 |
| Fraction unspliced | 0.718090154 |
| Fraction mitochondrial | 0.003818656 |
| H19.30.002 | 12733.0 |
| H19.30.001 | 12617.0 |
| H18.30.002 | 19015.0 |
| H18.30.001 | 1978.0 |
| Fraction cells from top donor | 0.410310079 |
| Number of donors | 4.0 |
| subcluster_id | None |