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CS202210140_129

ULIT_128 (CS202210140_129)

Hierarchy: CS202210140_476 > CS202210140_129

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_129


Labelset: Cluster (Rank: 1)

Parent Cell Set: Upper-layer intratelencephalic (CS202210140_476)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L2/3 IT https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:58570ade17 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 128
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1 VGLUT2
Neuropeptide auto_annotation ADCYAP CBLN CCK CHGA CHGB NAMPT NUCB SCG UBL VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L2/3 IT
Top three regions Cerebral cortex: 99.9%, Hypothalamus: 0.0%, Basal forebrain: 0.0%
Top three dissections Human M1C: 73.1%, Human S1C: 17.9%, Human A32: 4.1%
Top Enriched Genes AJ009632.2, MIR3976HG, LAMA2, TWIST1, VIPR2, AC087883.2, LINC02055, COL5A2, AL138694.1, SCTR
Number of cells 10650.0
DoubletFinder score 0.024745107
Total UMI 23508.71333
Fraction unspliced 0.707929811
Fraction mitochondrial 0.004109054
H19.30.002 2288.0
H19.30.001 2573.0
H18.30.002 5172.0
H18.30.001 617.0
Fraction cells from top donor 0.485633803
Number of donors 4.0
subcluster_id None