CS202210140_111
DLCT6b_110 (CS202210140_111)
Hierarchy: CS202210140_474 > CS202210140_111
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_111
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6 CT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:d4ee4a2c4c | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 110 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NPY NUCB SCG UBL proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6 CT |
| Top three regions | Cerebral cortex: 84.7%, Basal forebrain: 6.3%, Amygdala: 5.0% |
| Top three dissections | Human FI: 9.6%, Human ACC: 9.2%, Human A38: 7.1% |
| Top Enriched Genes | AC105021.1, TRIM22, SULF1, C5AR2, AC073968.2, LGR6, CAV1, AC079380.1, S100Z, ABCC9 |
| Number of cells | 8324.0 |
| DoubletFinder score | 0.020879009 |
| Total UMI | 29783.49652 |
| Fraction unspliced | 0.766942333 |
| Fraction mitochondrial | 0.003482217 |
| H19.30.002 | 2651.0 |
| H19.30.001 | 2807.0 |
| H18.30.002 | 2547.0 |
| H18.30.001 | 319.0 |
| Fraction cells from top donor | 0.337217684 |
| Number of donors | 4.0 |
| subcluster_id | None |