CS202210140_110
DLCT6b_109 (CS202210140_110)
Hierarchy: CS202210140_474 > CS202210140_110
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_110
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6 CT | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:d4ee4a2c4c | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 109 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB NXPH UBL proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6 CT |
| Top three regions | Cerebral cortex: 94.0%, Hippocampus: 3.3%, Basal forebrain: 1.8% |
| Top three dissections | Human M1C: 16.5%, Human MTG: 9.8%, Human TH-TL: 5.7% |
| Top Enriched Genes | AC105021.1, AC073968.2, VWA2, IL4R, C5AR2, SEMA3E, SH2D1B, ABCC9, SGCG, ADAMTSL1 |
| Number of cells | 10646.0 |
| DoubletFinder score | 0.016662874 |
| Total UMI | 24803.22393 |
| Fraction unspliced | 0.74081847 |
| Fraction mitochondrial | 0.002943878 |
| H19.30.002 | 3034.0 |
| H19.30.001 | 3672.0 |
| H18.30.002 | 2924.0 |
| H18.30.001 | 1016.0 |
| Fraction cells from top donor | 0.344918279 |
| Number of donors | 4.0 |
| subcluster_id | None |