CS202210140_107
DLCT6b_106 (CS202210140_107)
Hierarchy: CS202210140_474 > CS202210140_107
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_107
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6b | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:7b6e7cc097 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 106 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | ADCYAP CBLN CCK CHGA CHGB IGF NAMPT NUCB NXPH SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6b |
| Top three regions | Cerebral cortex: 99.0%, Hippocampus: 0.6%, Basal forebrain: 0.4% |
| Top three dissections | Human M1C: 20.6%, Human MTG: 8.8%, Human A23: 6.8% |
| Top Enriched Genes | AC023503.1, MDFIC, AC022133.2, AL138927.1, AC104689.2, DPP4, NPFFR2, KRT17, OLFML2B, CCN2 |
| Number of cells | 9905.0 |
| DoubletFinder score | 0.029031783 |
| Total UMI | 29076.03584 |
| Fraction unspliced | 0.721069398 |
| Fraction mitochondrial | 0.004149157 |
| H19.30.002 | 2566.0 |
| H19.30.001 | 3359.0 |
| H18.30.002 | 2984.0 |
| H18.30.001 | 996.0 |
| Fraction cells from top donor | 0.339121656 |
| Number of donors | 4.0 |
| subcluster_id | None |