CS202210140_106
DLCT6b_105 (CS202210140_106)
Hierarchy: CS202210140_474 > CS202210140_106
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_106
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6b | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:7b6e7cc097 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 105 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | ADCYAP CBLN CCK CHGA CHGB EDN IGF NAMPT NUCB NXPH SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6b |
| Top three regions | Cerebral cortex: 80.5%, Basal forebrain: 8.4%, Hippocampus: 7.2% |
| Top three dissections | Human ACC: 11.0%, Human FI: 10.2%, Human A25: 9.1% |
| Top Enriched Genes | AL138927.1, KRT17, CCN2, AC023503.1, MDFIC, AC104689.2, SNHG31, OLFML2B, AL358335.2, LINC01680 |
| Number of cells | 4269.0 |
| DoubletFinder score | 0.036189195 |
| Total UMI | 38693.1375 |
| Fraction unspliced | 0.743643418 |
| Fraction mitochondrial | 0.004010529 |
| H19.30.002 | 1115.0 |
| H19.30.001 | 1659.0 |
| H18.30.002 | 1317.0 |
| H18.30.001 | 178.0 |
| Fraction cells from top donor | 0.388615601 |
| Number of donors | 4.0 |
| subcluster_id | None |