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CS202210140_104

DLCT6b_103 (CS202210140_104)

Hierarchy: CS202210140_474 > CS202210140_104

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_104


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L6b https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:7b6e7cc097 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 103
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1
Neuropeptide auto_annotation ADCYAP CBLN CCK CHGA CHGB NAMPT NUCB NXPH PDYN SCG UBL VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L6b
Top three regions Cerebral cortex: 62.0%, Hippocampus: 25.8%, Amygdala: 12.1%
Top three dissections Human MEC: 45.4%, Human LEC: 14.7%, Human CA1U-CA2U-CA3U: 11.3%
Top Enriched Genes CCN2, AC092131.1, VWA2, GUCA1C, SLC15A5, ITPRID1, C12orf42, F2R, LINC01735, LINC02218
Number of cells 1268.0
DoubletFinder score 0.028890413
Total UMI 41470.72161
Fraction unspliced 0.75642845
Fraction mitochondrial 0.003289468
H19.30.002 313.0
H19.30.001 427.0
H18.30.002 521.0
H18.30.001 7.0
Fraction cells from top donor 0.410883281
Number of donors 4.0
subcluster_id None