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CS202210140_102

DLCT6b_101 (CS202210140_102)

Hierarchy: CS202210140_474 > CS202210140_102

PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_102


Labelset: Cluster (Rank: 1)

Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)

Cell Ontology Term:


Transferred annotations:

Transferred cell label Source taxonomy Source node accession Algorithm name Comment
L6b https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json CrossArea_subclass:7b6e7cc097 We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8.

Author annotation fields:

Author annotation Value
Cluster ID 101
Class auto_annotation NEUR
Neurotransmitter auto_annotation VGLUT1
Neuropeptide auto_annotation ADCYAP CBLN CCK CHGA CHGB IGF NAMPT NUCB NXPH PTHLH SCG UBL VGF proSAAS
Subtype auto_annotation None
Transferred MTG Label L6b
Top three regions Cerebral cortex: 65.6%, Hippocampus: 29.5%, Amygdala: 4.8%
Top three dissections Human MEC: 48.6%, Human Sub: 17.6%, Human LEC: 16.3%
Top Enriched Genes AC092131.1, CCN2, AL596257.1, AC064875.1, KRT17, AC005482.1, SNHG31, AP003100.2, OLFML2B, AC022133.2
Number of cells 2972.0
DoubletFinder score 0.021066037
Total UMI 43522.03096
Fraction unspliced 0.765220964
Fraction mitochondrial 0.002604994
H19.30.002 788.0
H19.30.001 1012.0
H18.30.002 1156.0
H18.30.001 16.0
Fraction cells from top donor 0.388963661
Number of donors 4.0
subcluster_id None