CS202210140_100
DLCT6b_99 (CS202210140_100)
Hierarchy: CS202210140_474 > CS202210140_100
PURL: https://purl.brain-bican.org/taxonomy/CS202210140/CS202210140_neurons/CS202210140_100
Labelset: Cluster (Rank: 1)
Parent Cell Set: Deep-layer corticothalamic and 6b (CS202210140_474)
Cell Ontology Term:
Transferred annotations:
| Transferred cell label | Source taxonomy | Source node accession | Algorithm name | Comment |
|---|---|---|---|---|
| L6b | https://purl.brain-bican.org/taxonomy/AIT_MTG/AIT_MTG.json | CrossArea_subclass:7b6e7cc097 | We performed PCA (50 components) on our full dataset, trained a random forest classifier (scikit-learn, class_ weight=‘balanced’, max_depth=50) on the MTG labels, and then predicted labels for all cells. We labeled each cluster with the mode of its constituent cells if two conditions were met: more than 0.8 of predicted labels matched the mode, and the mean probability of these pre- dictions was greater than 0.8. |
Author annotation fields:
| Author annotation | Value |
|---|---|
| Cluster ID | 99 |
| Class auto_annotation | NEUR |
| Neurotransmitter auto_annotation | VGLUT1 |
| Neuropeptide auto_annotation | CBLN CCK CHGA CHGB NAMPT NUCB NXPH SCG UBL UCN VGF proSAAS |
| Subtype auto_annotation | None |
| Transferred MTG Label | L6b |
| Top three regions | Cerebral cortex: 80.0%, Basal forebrain: 11.2%, Hippocampus: 6.5% |
| Top three dissections | Human FI: 11.3%, Human ACC: 10.3%, Human Cla: 8.0% |
| Top Enriched Genes | CCN2, VWA2, SLC15A5, AC092131.1, DPP4, CDH24, AL596257.1, AC002331.1, KRT17, ADTRP |
| Number of cells | 4421.0 |
| DoubletFinder score | 0.038247541 |
| Total UMI | 32273.87831 |
| Fraction unspliced | 0.735025717 |
| Fraction mitochondrial | 0.005623568 |
| H19.30.002 | 1520.0 |
| H19.30.001 | 1837.0 |
| H18.30.002 | 934.0 |
| H18.30.001 | 130.0 |
| Fraction cells from top donor | 0.415516851 |
| Number of donors | 4.0 |
| subcluster_id | None |